منابع مشابه
Autoantibodies in childhood scleroderma.
The clinical presentation of scleroderma in childhood is even more varied than in adult life. This study of 19 children shows that antinuclear antibodies (ANA) detected on the HEp2 cell substrate are just as common as in the adult disorders. All seven children with diffuse scleroderma or acrosclerosis were ANA positive, as were eight of the 12 with more localised disease. Antinucleolar antibodi...
متن کاملAutoantibodies against PDGF receptor in scleroderma.
n engl j med 354;25 www.nejm.org june 22, 2006 2709 Tashkin DP, Elashoff R, Clements PJ, et al. Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 2006;354:2655-66. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J 2005;26:948-68. Bouros D, Wells AU, Nicholson AG, et al. Histopathologic subsets of fibrosing alveoliti...
متن کاملAnti-IgE autoantibodies in systemic sclerosis (scleroderma).
An enzyme immunoassay was used to determine the prevalence of anti-IgE auto-antibodies in 66 patients with systemic sclerosis (scleroderma) stratified according to extent and duration of disease. Serum IgG anti-IgE antibodies were detected in 14 (21%) patients and IgM anti-IgE antibodies in nine (14%) patients. The overall prevalence of IgG or IgM isotypes was 21/66, (32%). Anti-IgE autoantibod...
متن کاملThe clinical relevance of autoantibodies in scleroderma
Scleroderma (systemic sclerosis) is associated with several autoantibodies, each of which is useful in the diagnosis of affected patients and in determining their prognosis. Anti-centromere antibodies (ACA) and anti-Scl-70 antibodies are very useful in distinguishing patients with systemic sclerosis (SSc) from healthy controls, from patients with other connective tissue disease, and from unaffe...
متن کاملAutoantibodies against matrix metalloproteinase-1 in patients with localized scleroderma.
BACKGROUND Localized scleroderma (LSc) is characterized by cutaneous fibrosis and various autoantibodies. OBJECTIVE To determine the presence or levels of antibodies (Abs) against matrix metalloproteinase (MMP)-1 and their clinical relevance in LSc. METHODS Anti-MMP-1 Ab was examined by ELISA (Enzyme-Linked ImmunoSorbent Assay) and immunoblotting using human recombinant MMP-1. MMP-1 collage...
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ژورنال
عنوان ژورنال: Ensho
سال: 1981
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.1.5_607